Granulomatosis with Polyangiitis (Wegener)

Definition

Granulomatosis with polyangiitis is a systemic vasculitis affecting the upper and lower respiratory tract and the kidneys.

Symptoms

  • nosebleeds
  • Sinusitis
  • Shortness of breath
  • Kidney failure

Reasons

Autoimmune mechanisms.

Diagnosis

ANCA testing, biopsy, imaging.

Treatment

Corticosteroids, cyclophosphamide, rituximab.

Which Polyclinic Should You Apply To?

Rheumatology Polyclinic

What to Do in an Emergency?

In case of respiratory failure, emergency services should be consulted.

This page is for general information purposes only.