Definition
Von Hippel-Lindau (VHL) disease is an autosomal dominant tumor syndrome characterized by the development of benign and malignant tumors in multiple organs.
Symptoms
- Central nervous system hemangioblastomas
- Retinal angiomas
- Kidney carcinoma
- Pheochromocytoma
Reasons
Mutation in the VHL tumor suppressor gene.
Diagnosis
Clinical criteria, genetic testing, regular screening (MRI, ultrasound).
Treatment
Surgery for tumors, radiosurgery, regular follow-up.
Which Polyclinic Should You Apply To?
Genetics Polyclinic or Oncology Polyclinic
What to Do in an Emergency?
In case of neurological deficit due to brain tumor or pheochromocytoma crisis, emergency department should be consulted.
This page is for general information purposes only.