Primary Myelofibrosis

Definition

Primary myelofibrosis is a myeloproliferative disease characterized by fibrosis of the bone marrow.

Symptoms

  • Weakness
  • Spleen enlargement
  • Anemia
  • Itching

Reasons

JAK2, CALR, or MPL mutations.

Diagnosis

Bone marrow biopsy, genetic testing.

Treatment

JAK inhibitors, transfusion, stem cell transplantation.

Which Polyclinic Should You Apply To?

Hematology Polyclinic

What to Do in an Emergency?

In case of severe spleen pain, emergency services should be consulted.

This page is for general information purposes only.