Pompe Disease

Definition

Pompe disease is a lysosomal storage disease characterized by progressive myopathy and cardiomyopathy, resulting from acid alpha-glucosidase enzyme deficiency.

Symptoms

  • Hypotonia
  • Cardiomegaly
  • Respiratory Failure
  • Progressive muscle weakness

Reasons

GAA gene mutation.

Diagnosis

Enzyme activity, genetic testing.

Treatment

Enzyme replacement therapy.

Which Polyclinic Should You Apply To?

Metabolism Polyclinic

What to Do in an Emergency?

In case of respiratory failure, emergency services should be consulted.

This page is for general information purposes only.