Pfeiffer Syndrome

Definition

Pfeiffer syndrome is a congenital syndrome characterized by craniosynostosis and broad thumbs and big toes.

Symptoms

  • Craniosynostosis
  • Broad thumbs
  • Facial hypoplasia
  • Hydrocephalus

Reasons

FGFR1 or FGFR2 gene mutations.

Diagnosis

Clinical findings, genetic testing.

Treatment

Surgical reconstruction.

Which Polyclinic Should You Apply To?

Genetics Polyclinic

What to Do in an Emergency?

In case of increased cranial pressure, emergency services should be consulted.

This page is for general information purposes only.