Definition
Paroxysmal nocturnal hemoglobinuria is a rare disease characterized by complement-mediated hemolysis due to PIG-A gene mutation.
Symptoms
- Dark urine
- Weakness
- Stomach ache
- Headache
Reasons
PIG-A gene mutation.
Diagnosis
Flow cytometry, LDH, haptoglobin.
Treatment
Eculizumab, corticosteroids, stem cell transplantation.
Which Polyclinic Should You Apply To?
Hematology Polyclinic
What to Do in an Emergency?
In case of severe hemolysis, emergency services should be consulted.
This page is for general information purposes only.