Nijmegen Fracture Syndrome

Definition

Nijmegen fracture syndrome is a rare autosomal recessive genetic disease characterized by microcephaly, immunodeficiency, cancer predisposition and radiosensitivity.

Symptoms

  • Microcephaly
  • Immunodeficiency
  • Increased risk of cancer
  • Radiosensitivity

Reasons

Mutation in the NBN gene.

Diagnosis

Clinical findings, genetic testing.

Treatment

Immunoglobulin replacement, cancer screening.

Which Polyclinic Should You Apply To?

Immunology Polyclinic

What to Do in an Emergency?

In case of severe infection, emergency services should be consulted.

This page is for general information purposes only.