Niemann-Pick Disease

Definition

Niemann-Pick disease is a lysosomal storage disease resulting from sphingomyelinase enzyme deficiency.

Symptoms

  • Liver and spleen enlargement
  • Neurological decline
  • Developmental delay
  • Cherry red macula

Reasons

SMPD1 gene mutation.

Diagnosis

Enzyme activity, genetic testing.

Treatment

Symptomatic treatment.

Which Polyclinic Should You Apply To?

Metabolism Polyclinic

What to Do in an Emergency?

In case of respiratory failure, emergency services should be consulted.

This page is for general information purposes only.