Nelson Syndrome

Definition

Nelson syndrome is the aggressive growth of an ACTH-secreting pituitary tumor that develops in patients who have undergone bilateral adrenalectomy for Cushing's disease.

Symptoms

  • Extreme darkening of the skin
  • Headache
  • Visual field loss
  • Signs of pituitary insufficiency

Reasons

Loss of feedback mechanism after bilateral adrenalectomy.

Diagnosis

High ACTH in the blood, tumor on pituitary MRI.

Treatment

Pituitary surgery, radiotherapy.

Which Polyclinic Should You Apply To?

Endocrinology Polyclinic or Neurosurgery Polyclinic

What to Do in an Emergency?

In case of sudden vision loss, emergency services should be consulted immediately.

This page is for general information purposes only.