Mucopolysaccharidosis Type IV (Morquio Syndrome)

Definition

Mucopolysaccharidosis type IV is a lysosomal storage disease characterized by keratan sulfate metabolism disorder, severe skeletal anomalies, and corneal opacity.

Symptoms

  • Serious skeletal abnormalities
  • Short stature
  • Corneal opacity
  • Cardiac involvement

Reasons

GALNS or GLB1 gene mutations.

Diagnosis

Urine GAG, enzyme activity.

Treatment

Enzyme replacement therapy.

Which Polyclinic Should You Apply To?

Metabolism Polyclinic

What to Do in an Emergency?

In case of respiratory distress, emergency services should be consulted.

This page is for general information purposes only.