Definition
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome characterized by tumors of the parathyroid, pancreas, and pituitary glands.
Symptoms
- Hyperparathyroidism (most common)
- Pancreatic neuroendocrine tumors (gastrinoma, insulinoma)
- Pituitary adenomas (prolactinomas)
- Facial angiofibromas
Reasons
Mutation in the MEN1 tumor suppressor gene.
Diagnosis
Clinical criteria, genetic testing, hormone screenings and imaging.
Treatment
Surgery, medical treatment, and regular screening for tumors.
Which Polyclinic Should You Apply To?
Endocrinology Polyclinic
What to Do in an Emergency?
In case of hypercalcemia crisis, hypoglycemia or ulcer bleeding, emergency services should be consulted.
This page is for general information purposes only.