Glycogen Storage Disease Type V (McArdle)

Definition

Glycogen storage disease type V is a metabolic disease characterized by muscle phosphorylase enzyme deficiency, exercise intolerance, and myoglobinuria.

Symptoms

  • Exercise intolerance
  • Muscle cramps
  • Myoglobinuria
  • Second wind phenomenon

Reasons

PYGM gene mutation.

Diagnosis

Muscle biopsy, genetic testing.

Treatment

Pre-exercise carbohydrate intake.

Which Polyclinic Should You Apply To?

Metabolism Polyclinic

What to Do in an Emergency?

In case of myoglobinuria and renal failure, emergency services should be consulted.

This page is for general information purposes only.