Carney Complex

Definition

Carney complex is a rare autosomal dominant genetic syndrome characterized by multiple myxomas, skin pigmentation, and various endocrine tumors.

Symptoms

  • Cardiac myxomas
  • Lentigines and bluish nevi on the skin
  • Primary pigmented nodular adrenal disease (PPNAD)
  • Pituitary adenomas

Reasons

Inactivating mutation in the PRKAR1A gene.

Diagnosis

Clinical criteria, genetic testing.

Treatment

Surgery for tumors, regular screening.

Which Polyclinic Should You Apply To?

Endocrinology Polyclinic or Genetics Polyclinic

What to Do in an Emergency?

In case of signs of embolism or obstruction due to cardiac myxoma, emergency department should be consulted.

This page is for general information purposes only.