Definition
Bartter syndrome is a rare autosomal recessive renal tubulopathy characterized by sodium and chloride malabsorption in the thick ascending limb of the loop of Henle.
Symptoms
- Polyuria, polydipsia
- Growth retardation
- Muscle weakness
- Dehydration
Reasons
Mutation in genes encoding ion channel proteins in the ascending limb of the loop of Henle.
Diagnosis
Low blood potassium and chloride, metabolic alkalosis, high plasma renin and aldosterone.
Treatment
Potassium supplements, NSAIDs (indomethacin), ACE inhibitors.
Which Polyclinic Should You Apply To?
Pediatric Nephrology Outpatient Clinic or Nephrology Polyclinic
What to Do in an Emergency?
In case of severe dehydration or hypokalemic paralysis, emergency services should be consulted.
This page is for general information purposes only.