Glycogen Storage Disease Type IV (Andersen)

Definition

Glycogen storage disease type IV is a rare metabolic disease characterized by branching enzyme deficiency, progressive liver cirrhosis, and neuromuscular involvement.

Symptoms

  • Hepatomegaly
  • Progressive cirrhosis
  • Hypotonia
  • Developmental delay

Reasons

GBE1 gene mutation.

Diagnosis

Liver biopsy, genetic testing.

Treatment

Liver transplantation.

Which Polyclinic Should You Apply To?

Metabolism Polyclinic

What to Do in an Emergency?

In case of liver failure, emergency services should be consulted.

This page is for general information purposes only.