{"id":21354,"date":"2025-11-17T01:45:46","date_gmt":"2025-11-16T22:45:46","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/nijmegen\/"},"modified":"2025-11-17T01:45:46","modified_gmt":"2025-11-16T22:45:46","slug":"nijmegen","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/nijmegen\/","title":{"rendered":"Nijmegen Fracture Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Nijmegen fracture syndrome is a rare autosomal recessive genetic disease characterized by microcephaly, immunodeficiency, cancer predisposition and radiosensitivity.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Microcephaly<\/li>\n<li>Immunodeficiency<\/li>\n<li>Increased risk of cancer<\/li>\n<li>Radiosensitivity<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Mutation in the NBN gene.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical findings, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Immunoglobulin replacement, cancer screening.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Immunology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of severe infection, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Nijmegen fracture syndrome is a rare autosomal recessive genetic disorder characterized by microcephaly, immunodeficiency, increased cancer risk, and radiosensitivity. Symptoms: Microcephaly, Immunodeficiency, Increased cancer risk, Radiosensitivity. Causes: Mutation in the NBN gene. Diagnosis: Clinical findings, genetic testing. Treatment: Immunoglobulin replacement, cancer screening. Which Clinic Should You Visit? Immunology Clinic. What to Do in an Emergency? In case of severe infection, seek emergency care [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Nijmegen Fracture Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Nijmegen fracture syndrome is a rare genetic disorder with autosomal recessive inheritance, characterized by microcephaly, immunodeficiency, cancer predisposition, and radiosensitivity."},"footnotes":""},"class_list":["post-21354","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21354","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21354\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}