{"id":21351,"date":"2025-11-17T01:45:46","date_gmt":"2025-11-16T22:45:46","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/dyskeratosis-congenita\/"},"modified":"2025-11-17T01:45:46","modified_gmt":"2025-11-16T22:45:46","slug":"dyskeratosis-congenita","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/dyskeratosis-congenita\/","title":{"rendered":"Dyskeratosis Congenita"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Dyskeratosis congenita is a rare genetic disease characterized by leukoplakia, nail dystrophy and skin pigmentation, with a risk of bone marrow failure and cancer.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Mucosal leukoplakia<\/li>\n<li>Nail dystrophy<\/li>\n<li>Reticular pigmentation of the skin<\/li>\n<li>Bone marrow failure<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Mutation in telomere maintenance genes.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical findings, genetic testing, telomere length measurement.<\/p>\n<h2>Treatment<\/h2>\n<p>Bone marrow transplantation, androgen therapy.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Hematology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of severe bleeding or infection, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Dyskeratosis congenita is a rare genetic disorder characterized by leukoplakia, nail dystrophy, and skin pigmentation, with an increased risk of bone marrow failure and cancer. Symptoms Mucosal leukoplakia Nail dystrophy Reticular pigmentation of the skin Bone marrow failure Causes Mutations in telomere maintenance genes. Diagnosis Clinical findings, genetic testing, telomere length measurement. Treatment Bone marrow transplantation, androgen therapy. Which Clinic Should You Consult? [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Dyskeratosis Congenita - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Dyskeratosis congenita is a rare genetic disorder characterized by leukoplakia, nail dystrophy, and skin pigmentation, with an increased risk of bone marrow failure and cancer."},"footnotes":""},"class_list":["post-21351","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21351","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21351\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21351"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}