{"id":21330,"date":"2025-11-17T01:45:45","date_gmt":"2025-11-16T22:45:45","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/vhl-hastaligi\/"},"modified":"2025-11-17T01:45:45","modified_gmt":"2025-11-16T22:45:45","slug":"vhl-hastaligi","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/vhl-hastaligi\/","title":{"rendered":"Von Hippel-Lindau (VHL) Disease"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Von Hippel-Lindau (VHL) disease is an autosomal dominant tumor syndrome characterized by the development of benign and malignant tumors in multiple organs.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Central nervous system hemangioblastomas<\/li>\n<li>Retinal angiomas<\/li>\n<li>Kidney carcinoma<\/li>\n<li>Pheochromocytoma<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Mutation in the VHL tumor suppressor gene.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical criteria, genetic testing, regular screening (MRI, ultrasound).<\/p>\n<h2>Treatment<\/h2>\n<p>Surgery for tumors, radiosurgery, regular follow-up.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Genetics Polyclinic<\/strong> or <strong>Oncology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of neurological deficit due to brain tumor or pheochromocytoma crisis, emergency department should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Von Hippel-Lindau (VHL) disease is an autosomal dominant tumor syndrome characterized by the development of benign and malignant tumors in multiple organs. Symptoms Central nervous system hemangioblastomas Retinal angiomas Kidney carcinoma Pheochromocytoma Causes Mutation in the VHL tumor suppressor gene. Diagnosis Clinical criteria, genetic testing, routine screening (MRI, ultrasound). Treatment Tumor-specific surgery, radiosurgery, regular follow-up. Which Clinic Should You Consult? [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Von Hippel-Lindau (VHL) Disease - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Von Hippel-Lindau (VHL) disease is an autosomal dominant tumor syndrome characterized by the development of benign and malignant tumors in multiple organs."},"footnotes":""},"class_list":["post-21330","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21330","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21330\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21330"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}