{"id":21323,"date":"2025-11-17T01:45:45","date_gmt":"2025-11-16T22:45:45","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/pseudohipoaldosteronizm\/"},"modified":"2025-11-17T01:45:45","modified_gmt":"2025-11-16T22:45:45","slug":"pseudohipoaldosteronizm","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/pseudohipoaldosteronizm\/","title":{"rendered":"Pseudohypoaldosteronism Type 1"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Pseudohypoaldosteronism type 1 is a rare disease characterized by salt wasting, hyperkalemia and metabolic acidosis as a result of kidney resistance to aldosterone hormone.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Vomiting<\/li>\n<li>Dehydration<\/li>\n<li>Growth retardation<\/li>\n<li>Hyperkalemia<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Mineralocorticoid receptor mutation (autosomal dominant) or epithelial sodium channel (ENaC) mutations (autosomal recessive).<\/p>\n<h2>Diagnosis<\/h2>\n<p>High aldosterone and renin in the blood, hyperkalemia, hyponatremia.<\/p>\n<h2>Treatment<\/h2>\n<p>High-dose salt replacement, sodium polystyrene sulfonate (for hyperkalaemia).<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Pediatric Endocrinology Polyclinic<\/strong> or <strong>Pediatric Nephrology Outpatient Clinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of severe hyperkalemia (muscle weakness, risk of cardiac arrhythmia), emergency services should be consulted immediately.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Pseudohypoaldosteronism type 1 is a rare disease characterized by salt loss, hyperkalemia, and metabolic acidosis due to resistance of the kidneys to the hormone aldosterone. Symptoms Vomiting Dehydration Growth retardation Hyperkalemia Causes Mineralocorticoid receptor mutation (autosomal dominant) or epithelial sodium channel (ENaC) mutations (autosomal recessive). Diagnosis High blood aldosterone and renin levels, hyperkalemia, hyponatremia. Treatment High-dose salt replacement, sodium polystyrene [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Pseudohypoaldosteronism Type 1 - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Pseudohypoaldosteronism type 1 is a rare disease characterized by salt wasting, hyperkalemia, and metabolic acidosis due to resistance of the kidneys to the hormone aldosterone."},"footnotes":""},"class_list":["post-21323","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21323","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21323\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21323"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}