{"id":21283,"date":"2025-11-17T01:45:44","date_gmt":"2025-11-16T22:45:44","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/tirozinemi\/"},"modified":"2025-11-17T01:45:44","modified_gmt":"2025-11-16T22:45:44","slug":"tirozinemi","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/tirozinemi\/","title":{"rendered":"Tyrosinemia Type I"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Tyrosinemia type I is a metabolic disease characterized by fumarylacetoacetase enzyme deficiency, accompanied by liver failure and renal tubular dysfunction.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Liver failure<\/li>\n<li>Renal Fanconi syndrome<\/li>\n<li>Neurological crises<\/li>\n<li>Hypertrophic cardiomyopathy<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>FAH gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Plasma tyrosine, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>NTBC, dietary restriction.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of liver failure, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Tyrosinemia type I is a metabolic disease characterized by fumarilacetoacetase enzyme deficiency, resulting in liver failure and renal tubular dysfunction. Symptoms: Liver failure, Renal Fanconi syndrome, Neurological crises, Hypertrophic cardiomyopathy. Causes: FAH gene mutation. Diagnosis: Plasma tyrosine, genetic testing. Treatment: NTBC, dietary restriction. Which Clinic Should You Visit? Metabolism Clinic. What to Do in an Emergency? In case of liver failure [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Tyrosinemia Type I - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Tyrosinemia type I is a metabolic disease characterized by fumarilacetoacetase enzyme deficiency, resulting in liver failure and renal tubular dysfunction."},"footnotes":""},"class_list":["post-21283","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21283","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21283\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}