{"id":21279,"date":"2025-11-17T01:45:44","date_gmt":"2025-11-16T22:45:44","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/methylmalonic\/"},"modified":"2025-11-17T01:45:44","modified_gmt":"2025-11-16T22:45:44","slug":"methylmalonic","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/methylmalonic\/","title":{"rendered":"Methylmalonic Acidemia"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Methylmalonic acidemia is an organic acidemia characterized by methylmalonyl-CoA mutase enzyme deficiency, accompanied by metabolic acidosis and hyperammonemia.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Metabolic acidosis<\/li>\n<li>Hyperammonemia<\/li>\n<li>Vomiting<\/li>\n<li>Lethargy<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>MUT gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Urine organic acids, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Dietary restriction, B12, L-carnitine.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of metabolic crisis, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Methylmalonic acidemia is an organic acidemia characterized by metabolic acidosis and hyperammonemia due to methylmalonyl-CoA mutase enzyme deficiency. Symptoms: Metabolic acidosis, hyperammonemia, vomiting, lethargy. Causes: MUT gene mutation. Diagnosis: Urinary organic acids, genetic testing. Treatment: Dietary restriction, B12, L-carnitine. Which Clinic Should You Go To? Metabolism Clinic. What to Do in an Emergency? In case of a metabolic crisis, go to the emergency room. This page [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Methylmalonic Acidemia - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Methylmalonic acidemia is an organic acidemia characterized by metabolic acidosis and hyperammonemia, resulting from a deficiency in the methylmalonyl-CoA mutase enzyme. Symptoms"},"footnotes":""},"class_list":["post-21279","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21279\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}