{"id":21266,"date":"2025-11-17T01:45:44","date_gmt":"2025-11-16T22:45:44","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/leigh\/"},"modified":"2025-11-17T01:45:44","modified_gmt":"2025-11-16T22:45:44","slug":"leigh","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/leigh\/","title":{"rendered":"Leigh Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Leigh syndrome is a mitochondrial disease characterized by progressive neurological impairment, lactic acidosis, and brainstem involvement.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Neurological decline<\/li>\n<li>Lactic acidosis<\/li>\n<li>Nystagmus<\/li>\n<li>Respiratory Failure<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Various mitochondrial enzyme defects.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Brain MRI, lactate level, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Symptomatic treatment.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of respiratory failure, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Leigh syndrome is a mitochondrial disorder characterized by progressive neurological impairment, lactic acidosis, and brainstem involvement. Symptoms Neurological regression Lactic acidosis Nystagmus Respiratory failure Causes Various mitochondrial enzyme defects. Diagnosis Brain MRI, lactate level, genetic testing. Treatment Symptomatic treatment. Which Clinic Should You Go To? Metabolism Clinic What to Do in an Emergency? In case of respiratory failure, go to the emergency room. [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Leigh Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Leigh syndrome is a mitochondrial disorder characterized by progressive neurological impairment, lactic acidosis, and brainstem involvement. Symptoms: Neurological impairment"},"footnotes":""},"class_list":["post-21266","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21266","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21266\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}