{"id":21263,"date":"2025-11-17T01:45:43","date_gmt":"2025-11-16T22:45:43","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/piruvat-kinaz\/"},"modified":"2025-11-17T01:45:43","modified_gmt":"2025-11-16T22:45:43","slug":"piruvat-kinaz","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/piruvat-kinaz\/","title":{"rendered":"Pyruvate Kinase Deficiency"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Pyruvate kinase deficiency is the most common enzymopathic hemolytic anemia, characterized by hemolytic anemia, splenomegaly, and hyperbilirubinemia.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Hemolytic anemia<\/li>\n<li>Splenomegaly<\/li>\n<li>Hyperbilirubinemia<\/li>\n<li>Fatigue<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>PKLR gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Enzyme activity, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Folic acid, splenectomy.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Hematology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of severe anemia, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Pyruvate kinase deficiency is the most common enzymatic hemolytic anemia, characterized by hemolytic anemia, splenomegaly, and hyperbilirubinemia. Symptoms: Hemolytic anemia, Splenomegaly, Hyperbilirubinemia, Fatigue. Causes: PKLR gene mutation. Diagnosis: Enzyme activity, genetic testing. Treatment: Folic acid, splenectomy. Which Clinic Should You Go To? Hematology Clinic. What to Do in an Emergency? In case of severe anemia, go to the emergency room. This page provides general information [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Pyruvate Kinase Deficiency - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Pyruvate kinase deficiency is the most common enzymapathic hemolytic anemia, characterized by hemolytic anemia, splenomegaly, and hyperbilirubinemia. Symptoms: Hemo"},"footnotes":""},"class_list":["post-21263","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21263\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}