{"id":21255,"date":"2025-11-17T01:45:43","date_gmt":"2025-11-16T22:45:43","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/mcardle\/"},"modified":"2025-11-17T01:45:43","modified_gmt":"2025-11-16T22:45:43","slug":"mcardle","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/mcardle\/","title":{"rendered":"Glycogen Storage Disease Type V (McArdle)"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Glycogen storage disease type V is a metabolic disease characterized by muscle phosphorylase enzyme deficiency, exercise intolerance, and myoglobinuria.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Exercise intolerance<\/li>\n<li>Muscle cramps<\/li>\n<li>Myoglobinuria<\/li>\n<li>Second wind phenomenon<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>PYGM gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Muscle biopsy, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Pre-exercise carbohydrate intake.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of myoglobinuria and renal failure, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Glycogen storage disease type V is a metabolic disease characterized by muscle phosphorylase enzyme deficiency, exercise intolerance, and myoglobinuria. Symptoms Exercise intolerance Muscle cramps Myoglobinuria Second wind phenomenon Causes PYGM gene mutation. Diagnosis Muscle biopsy, genetic testing. Treatment Pre-exercise carbohydrate intake. Which Clinic Should You Consult? Metabolism Clinic What to Do in an Emergency? Myoglobinuria and [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Glycogen Storage Disease Type V (McArdle) - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Glycogen storage disease type V is a metabolic disorder characterized by muscle phosphorylase enzyme deficiency, accompanied by exercise intolerance and myoglobinuria."},"footnotes":""},"class_list":["post-21255","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21255\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}