{"id":21246,"date":"2025-11-17T01:45:43","date_gmt":"2025-11-16T22:45:43","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/gangliosidosis\/"},"modified":"2025-11-17T01:45:43","modified_gmt":"2025-11-16T22:45:43","slug":"gangliosidosis","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/gangliosidosis\/","title":{"rendered":"Gangliosidosis"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Gangliosidosis is a lysosomal storage disease characterized by disorders of ganglioside metabolism and progressive neurological disorders.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Neurological decline<\/li>\n<li>Macrocephaly<\/li>\n<li>Cherry red macula<\/li>\n<li>Hypotonia<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>HEXA, GLB1 gene mutations.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Enzyme activity, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Symptomatic treatment.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of status epilepticus, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Gangliosidosis is a lysosomal storage disorder characterized by progressive neurological impairment due to abnormalities in ganglioside metabolism. Symptoms Neurological regression Macrocephaly Cherry-red macula Hypotonia Causes HEXA, GLB1 gene mutations. Diagnosis Enzyme activity, genetic testing. Treatment Symptomatic treatment. Which Clinic Should You Go To? Metabolism Clinic What to Do in an Emergency? In case of status epilepticus, go to the emergency room. This page provides general information [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Gangliosidosis - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Gangliosidosis is a lysosomal storage disorder characterized by progressive neurological impairment due to abnormalities in ganglioside metabolism. Symptoms"},"footnotes":""},"class_list":["post-21246","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21246\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}