{"id":21242,"date":"2025-11-17T01:45:43","date_gmt":"2025-11-16T22:45:43","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/morquio\/"},"modified":"2025-11-17T01:45:43","modified_gmt":"2025-11-16T22:45:43","slug":"morquio","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/morquio\/","title":{"rendered":"Mucopolysaccharidosis Type IV (Morquio Syndrome)"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Mucopolysaccharidosis type IV is a lysosomal storage disease characterized by keratan sulfate metabolism disorder, severe skeletal anomalies, and corneal opacity.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Serious skeletal abnormalities<\/li>\n<li>Short stature<\/li>\n<li>Corneal opacity<\/li>\n<li>Cardiac involvement<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>GALNS or GLB1 gene mutations.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Urine GAG, enzyme activity.<\/p>\n<h2>Treatment<\/h2>\n<p>Enzyme replacement therapy.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of respiratory distress, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Mucopolysaccharidosis type IV is a lysosomal storage disease characterized by keratan sulfate metabolism disorder, resulting in severe skeletal abnormalities and corneal opacity. Symptoms: Severe skeletal abnormalities, short stature, corneal opacity, cardiac involvement. Causes: GALNS or GLB1 gene mutations. Diagnosis: Urinary GAG, enzyme activity. Treatment: Enzyme replacement therapy. Which Clinic to Visit? Metabolism Clinic. What to Do in an Emergency? [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Mucopolysaccharidosis Type IV (Morquio Syndrome) - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Mucopolysaccharidosis type IV is a lysosomal disorder characterized by impaired keratan sulfate metabolism, resulting in severe skeletal abnormalities and corneal opacity."},"footnotes":""},"class_list":["post-21242","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21242\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}