{"id":21184,"date":"2025-11-17T01:45:42","date_gmt":"2025-11-16T22:45:42","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/costello\/"},"modified":"2025-11-17T01:45:42","modified_gmt":"2025-11-16T22:45:42","slug":"costello","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/costello\/","title":{"rendered":"Costello Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Costello syndrome is an inherited disorder characterized by coarse facial appearance, skin laxity, and risk of cancer.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Rough facial appearance<\/li>\n<li>Skin laxity<\/li>\n<li>Developmental delay<\/li>\n<li>Cancer risk<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>HRAS gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical findings, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Symptomatic treatment.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Genetics Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of cardiac complications, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Costello syndrome is a hereditary disorder characterized by coarse facial features, skin laxity, and an increased risk of cancer. Symptoms Coarse facial features Skin laxity Developmental delay Cancer risk Causes HRAS gene mutation. Diagnosis Clinical findings, genetic testing. Treatment Symptomatic treatment. Which Clinic Should You Go To? Genetics Clinic What to Do in an Emergency? In case of cardiac complications, go to the emergency room. This page [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Costello Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Costello syndrome is a hereditary disorder characterized by a coarse facial appearance, skin laxity, and an increased risk of cancer. Symptoms: Coarse facial appearance, skin laxity."},"footnotes":""},"class_list":["post-21184","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21184","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21184\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21184"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}