{"id":21182,"date":"2025-11-17T01:45:45","date_gmt":"2025-11-16T22:45:45","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/cohen\/"},"modified":"2025-11-17T01:45:45","modified_gmt":"2025-11-16T22:45:45","slug":"cohen-sendromu","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/cohen-sendromu\/","title":{"rendered":"Cohen Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Cohen syndrome is a rare autosomal recessive genetic syndrome characterized by obesity, hypotonia, mental retardation, characteristic facial appearance and neutropenia.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Developmental delay and mental retardation<\/li>\n<li>Progressive retinal dystrophy<\/li>\n<li>Neutropenia<\/li>\n<li>Obesity (body)<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Mutation in the VPS13B gene.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical findings, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Supportive treatment (physical therapy, special education), neutropenia monitoring.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Genetics Polyclinic<\/strong> or <strong>Pediatrics Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of serious infection (due to neutropenia), emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Cohen syndrome is a rare autosomal recessive genetic syndrome characterized by obesity, hypotonia, mental retardation, characteristic facial features, and neutropenia. Symptoms: Developmental delay and mental retardation, Progressive retinal dystrophy, Neutropenia, Obesity (trunk). Causes: Mutation in the VPS13B gene. Diagnosis: Clinical findings, genetic testing. Treatment: Supportive treatment (physical therapy, special education), monitoring of neutropenia. Which Clinic to Consult? Genetic [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Cohen Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Cohen syndrome is a rare genetic disorder with autosomal recessive inheritance, characterized by obesity, hypotonia, mental retardation, characteristic facial features, and neutropenia."},"footnotes":""},"class_list":["post-21182","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":1,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21182\/revisions"}],"predecessor-version":[{"id":21343,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21182\/revisions\/21343"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}