{"id":21180,"date":"2025-11-17T01:45:42","date_gmt":"2025-11-16T22:45:42","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/alagille\/"},"modified":"2025-11-17T01:45:42","modified_gmt":"2025-11-16T22:45:42","slug":"alagille","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/alagille\/","title":{"rendered":"Alagille Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Alagille syndrome is an inherited disorder characterized by bile duct paucity, congenital heart disease, and characteristic facial appearance.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Bile duct deficiency<\/li>\n<li>Peripheral pulmonary stenosis<\/li>\n<li>Butterfly vertebra<\/li>\n<li>Characteristic face<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>JAG1 or NOTCH2 gene mutations.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical criteria, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Symptomatic treatment, liver transplantation.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Gastroenterology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of symptoms of liver failure, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Alagille syndrome is a hereditary disease characterized by bile duct obstruction, congenital heart disease, and a characteristic facial appearance. Symptoms: Bile duct obstruction, Peripheral pulmonary stenosis, Butterfly vertebrae, Characteristic facial features. Causes: JAG1 or NOTCH2 gene mutations. Diagnosis: Clinical criteria, genetic testing. Treatment: Symptomatic treatment, liver transplant. Which Clinic Should You Visit? Gastroenterology Clinic. What to Do in an Emergency? Liver [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Alagille Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Alagille syndrome is a hereditary disorder characterized by bile duct deficiency, congenital heart disease, and a characteristic facial appearance. Symptoms: Bile"},"footnotes":""},"class_list":["post-21180","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21180","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21180\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21180"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}