{"id":21167,"date":"2025-11-17T01:45:42","date_gmt":"2025-11-16T22:45:42","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/holt-oram\/"},"modified":"2025-11-17T01:45:42","modified_gmt":"2025-11-16T22:45:42","slug":"holt-oram","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/holt-oram\/","title":{"rendered":"Holt-Oram Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Holt-Oram syndrome is an inherited syndrome characterized by congenital heart defects and upper extremity anomalies.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Atrial septal defect<\/li>\n<li>Radial ray anomalies<\/li>\n<li>Pectoral muscle hypoplasia<\/li>\n<li>Cardiac conduction defects<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>TBX5 gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical findings, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Cardiac surgery, orthopedic treatment.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Genetics Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of symptoms of heart failure, emergency services should be sought.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Holt-Oram syndrome is a hereditary syndrome characterized by congenital heart defects and upper extremity anomalies. Symptoms: Atrial septal defect, radial ray anomalies, pectoral muscle hypoplasia, cardiac conduction defects. Causes: TBX5 gene mutation. Diagnosis: Clinical findings, genetic testing. Treatment: Cardiac surgery, orthopedic treatment. Which Clinic Should You Visit? Genetics Clinic. What to Do in an Emergency? In case of symptoms of heart failure [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Holt-Oram Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Holt-Oram syndrome is a hereditary syndrome characterized by congenital heart defects and upper extremity anomalies. Symptoms: Atrial septal defect (RAD)"},"footnotes":""},"class_list":["post-21167","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21167","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21167\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21167"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}