{"id":21152,"date":"2025-11-17T01:45:45","date_gmt":"2025-11-16T22:45:45","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/men2\/"},"modified":"2025-11-17T01:45:45","modified_gmt":"2025-11-16T22:45:45","slug":"men2","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/men2\/","title":{"rendered":"Multiple Endocrine Neoplasia Type 2 (MEN2)"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant syndrome characterized by medullary thyroid cancer, pheochromocytoma, and hyperparathyroidism.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Med\u00fcller tiroid karsinomu (%100)<\/li>\n<li>Feokromositoma (%50)<\/li>\n<li>Hiperparatiroidi (%20-30)<\/li>\n<li>Mucosal neuromas in MEN2B<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Activating mutation in the RET proto-oncogene.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Genetic testing, calcitonin, catecholamine screening.<\/p>\n<h2>Treatment<\/h2>\n<p>Prophylactic thyroidectomy, pheochromocytoma surgery.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Endocrinology Polyclinic<\/strong> or <strong>Genetics Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of hypertensive crisis (pheochromocytoma), emergency services should be consulted immediately.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Tan\u0131m Multiple endokrin neoplazi tip 2 (MEN2), med\u00fcller tiroid kanseri, feokromositoma ve hiperparatiroidi ile karakterize otozomal dominant ge\u00e7i\u015fli bir sendromdur. Belirtiler Med\u00fcller tiroid karsinomu (%100) Feokromositoma (%50) Hiperparatiroidi (%20-30) MEN2B&#8217;de muk\u00f6zan n\u00f6romlar Sebepler RET proto-onkogeninde aktive edici mutasyon. Tan\u0131 Genetik test, kalsitonin, katekolamin taramas\u0131. Tedavi Profilaktik tiroidektomi, feokromositoma cerrahisi. Hangi Poliklini\u011fe Ba\u015fvurulmal\u0131? Endokrinoloji Poliklini\u011fi veya [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Multiple Endocrine Neoplasia Type 2 (MEN2) - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant syndrome characterized by medullary thyroid cancer, pheochromocytoma, and hyperparathyroidism."},"footnotes":""},"class_list":["post-21152","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":1,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21152\/revisions"}],"predecessor-version":[{"id":21329,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21152\/revisions\/21329"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}