{"id":21151,"date":"2025-11-17T01:45:45","date_gmt":"2025-11-16T22:45:45","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/men1\/"},"modified":"2025-11-17T01:45:45","modified_gmt":"2025-11-16T22:45:45","slug":"men1","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/men1\/","title":{"rendered":"Multiple Endocrine Neoplasia Type 1 (MEN1)"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome characterized by tumors of the parathyroid, pancreas, and pituitary glands.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Hyperparathyroidism (most common)<\/li>\n<li>Pancreatic neuroendocrine tumors (gastrinoma, insulinoma)<\/li>\n<li>Pituitary adenomas (prolactinomas)<\/li>\n<li>Facial angiofibromas<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Mutation in the MEN1 tumor suppressor gene.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical criteria, genetic testing, hormone screenings and imaging.<\/p>\n<h2>Treatment<\/h2>\n<p>Surgery, medical treatment, and regular screening for tumors.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Endocrinology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of hypercalcemia crisis, hypoglycemia or ulcer bleeding, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome characterized by tumors of the parathyroid, pancreas, and pituitary glands. Symptoms Hyperparathyroidism (most common) Pancreatic neuroendocrine tumors (gastrinoma, insulinoma) Pituitary adenomas (prolactinoma) Facial angiofibromas Causes Mutation in the MEN1 tumor suppressor gene. Diagnosis Clinical criteria, genetic testing, hormone screenings, and imaging. Treatment Surgery targeting the tumors, medical treatment, [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Multiple Endocrine Neoplasia Type 1 (MEN1) - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome characterized by tumors of the parathyroid, pancreas, and pituitary glands."},"footnotes":""},"class_list":["post-21151","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21151","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":1,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21151\/revisions"}],"predecessor-version":[{"id":21328,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21151\/revisions\/21328"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21151"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}