{"id":21143,"date":"2025-11-17T01:45:41","date_gmt":"2025-11-16T22:45:41","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/lynch\/"},"modified":"2025-11-17T01:45:41","modified_gmt":"2025-11-16T22:45:41","slug":"lynch","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/lynch\/","title":{"rendered":"Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome)"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Lynch syndrome is an inherited syndrome characterized by an increased risk of colorectal and endometrial cancer.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Colorectal cancer at an early age<\/li>\n<li>Endometrial cancer<\/li>\n<li>Family history<\/li>\n<li>Mismatch repair gene mutations<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>MLH1, MSH2, MSH6, PMS2 gene mutations.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Genetic testing, immunohistochemistry.<\/p>\n<h2>Treatment<\/h2>\n<p>Cancer screening, prophylactic surgery.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Oncology Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of cancer emergencies, the emergency room should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Lynch syndrome is a hereditary syndrome characterized by an increased risk of colorectal and endometrial cancer. Symptoms: Colorectal cancer at an early age, Endometrial cancer, Family history, Mismatch repair gene mutations. Causes: MLH1, MSH2, MSH6, PMS2 gene mutations. Diagnosis: Genetic testing, immunohistochemistry. Treatment: Cancer screening, prophylactic surgery. Which Clinic Should You Go To? Oncology Clinic. What to Do in an Emergency? In case of cancer emergencies [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Lynch syndrome is a hereditary syndrome characterized by an increased risk of colorectal and endometrial cancer. Symptoms: Colorectal cancer at an early age; Endometrial cancer"},"footnotes":""},"class_list":["post-21143","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21143\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}