{"id":21132,"date":"2025-11-17T01:45:45","date_gmt":"2025-11-16T22:45:45","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/prader-willi\/"},"modified":"2025-11-17T01:45:45","modified_gmt":"2025-11-16T22:45:45","slug":"prader-willi","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/prader-willi\/","title":{"rendered":"Prader-Willi Syndrome"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Prader-Willi syndrome is a genetic disease characterized by hypotonic infantile period, obesity due to hyperphagia, short stature, hypogonadism and learning difficulties.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Severe hypotonia and feeding difficulties in infancy<\/li>\n<li>Excessive appetite and obesity in childhood<\/li>\n<li>Short stature, small hands and feet<\/li>\n<li>Behavioral problems<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>Deletion of paternal genes in the q11-q13 region of chromosome 15, or uniparental disomy.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Clinical criteria, methylation test.<\/p>\n<h2>Treatment<\/h2>\n<p>Growth hormone therapy, behavioral therapy, strict dietary control.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Pediatric Endocrinology Polyclinic<\/strong> or <strong>Genetics Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of respiratory distress due to obesity or diabetic ketoacidosis, the emergency room should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition Prader-Willi syndrome is a genetic disorder characterized by hypotonic infantile development, obesity due to hyperphagia, short stature, hypogonadism, and learning disabilities. Symptoms Severe hypotonia and feeding difficulties in infancy Excessive appetite and obesity in childhood Short stature, small hands and feet Behavioral problems Causes Deletion of paternal genes in the q11-q13 region of chromosome 15 or uniparental disomy. Diagnosis Clinical criteria, methylation [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Prader-Willi Syndrome - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Prader-Willi syndrome is a genetic disorder characterized by hypotonic infancy, obesity due to hyperphagia, short stature, hypogonadism, and learning disabilities."},"footnotes":""},"class_list":["post-21132","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":2,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21132\/revisions"}],"predecessor-version":[{"id":21337,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21132\/revisions\/21337"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}