{"id":21122,"date":"2025-11-17T01:45:40","date_gmt":"2025-11-16T22:45:40","guid":{"rendered":"https:\/\/hastane.ksu.edu.tr\/hastaliklar\/niemann-pick\/"},"modified":"2025-11-17T01:45:40","modified_gmt":"2025-11-16T22:45:40","slug":"niemann-pick","status":"publish","type":"hastaliklar","link":"https:\/\/hastane.ksu.edu.tr\/en\/hastaliklar\/niemann-pick\/","title":{"rendered":"Niemann-Pick Disease"},"content":{"rendered":"<h2>Definition<\/h2>\n<p>Niemann-Pick disease is a lysosomal storage disease resulting from sphingomyelinase enzyme deficiency.<\/p>\n<h2>Symptoms<\/h2>\n<ul>\n<li>Liver and spleen enlargement<\/li>\n<li>Neurological decline<\/li>\n<li>Developmental delay<\/li>\n<li>Cherry red macula<\/li>\n<\/ul>\n<h2>Reasons<\/h2>\n<p>SMPD1 gene mutation.<\/p>\n<h2>Diagnosis<\/h2>\n<p>Enzyme activity, genetic testing.<\/p>\n<h2>Treatment<\/h2>\n<p>Symptomatic treatment.<\/p>\n<h2>Which Polyclinic Should You Apply To?<\/h2>\n<p><strong>Metabolism Polyclinic<\/strong><\/p>\n<h2>What to Do in an Emergency?<\/h2>\n<p>In case of respiratory failure, emergency services should be consulted.<\/p>\n<p><em>This page is for general information purposes only.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Definition: Niemann-Pick disease is a lysosomal storage disease resulting from sphingomyelinase enzyme deficiency. Symptoms: Enlargement of the liver and spleen, neurological regression, developmental delay, cherry-red macula. Causes: SMPD1 gene mutation. Diagnosis: Enzyme activity, genetic testing. Treatment: Symptomatic treatment. Which Clinic Should You Go To? Metabolism Clinic. What to Do in an Emergency? In case of respiratory failure, go to the emergency room. This page is for general information purposes only [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"slim_seo":{"title":"Niemann-Pick Disease - Kahramanmara\u015f S\u00fct\u00e7\u00fc \u0130mam University Health Practice and Research Hospital","description":"Definition: Niemann-Pick disease is a lysosomal storage disease resulting from a deficiency of the sphingomyelinase enzyme. Symptoms: Enlargement of the liver and spleen; Neurological retardation."},"footnotes":""},"class_list":["post-21122","hastaliklar","type-hastaliklar","status-publish","format-standard","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar"}],"about":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/types\/hastaliklar"}],"author":[{"embeddable":true,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/hastaliklar\/21122\/revisions"}],"wp:attachment":[{"href":"https:\/\/hastane.ksu.edu.tr\/en\/wp-json\/wp\/v2\/media?parent=21122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}